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Best NCAAB 2025-26 March Madness - Second Round Sports Betting Odds - Compare Live Lines & Odds | Tallysight
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Today, March 21
NCAAB • Saint Louis Billikens @ Michigan Wolverines • Midwest Regional - Second Round - Game 1
NCAAB • SLU @ MICH
3/21 • 4:10PM
Sat, Mar 21 • 4:10PM
Saint Louis Billikens
SLU
3
Michigan Wolverines
3
MICH
Moneyline
Moneyline
13%
13%
88%
88%
Spread
Spread
+12.5
+12.5
51%
51%
-12.5
-12.5
50%
50%
Total
Total
O 161.5
O 161.5
50%
50%
U 161.5
U 161.5
51%
51%
J
T
2 picks
100%
predict
SLU
will cover the spread
More markets
Updated
8 minutes ago
NCAAB • Louisville Cardinals @ Michigan State Spartans • East Regional - Second Round - Game 3
NCAAB • LOU @ MSU
3/21 • 6:45PM
Sat, Mar 21 • 6:45PM
24
Louisville Cardinals
24
LOU
11
Michigan State Spartans
11
MSU
Moneyline
Moneyline
36%
36%
65%
65%
Spread
Spread
+4.5
+4.5
50%
50%
-4.5
-4.5
52%
52%
Total
Total
O 151.5
O 151.5
50%
50%
U 151.5
U 151.5
51%
51%
J
1 pick
100%
predict
LOU
will cover the spread
More markets
Updated
8 minutes ago
NCAAB • TCU Horned Frogs @ Duke Blue Devils • East Regional - Second Round - Game 1
NCAAB • TCU @ DUKE
3/21 • 9:15PM
Sat, Mar 21 • 9:15PM
TCU Horned Frogs
TCU
1
Duke Blue Devils
1
DUKE
Moneyline
Moneyline
14%
14%
87%
87%
Spread
Spread
+11.5
+11.5
49%
49%
-11.5
-11.5
52%
52%
Total
Total
O 140.5
O 140.5
50%
50%
U 140.5
U 140.5
51%
51%
J
1 pick
100%
predict
DUKE
will cover the spread
More markets
Updated
8 minutes ago
NCAAB • Texas A&M Aggies @ Houston Cougars • South Regional - Second Round - Game 4
NCAAB • TAMU @ HOU
3/21 • 10:10PM
Sat, Mar 21 • 10:10PM
Texas A&M Aggies
TAMU
5
Houston Cougars
5
HOU
Moneyline
Moneyline
18%
18%
83%
83%
Spread
Spread
+10.5
+10.5
49%
49%
-10.5
-10.5
52%
52%
Total
Total
O 142.5
O 142.5
50%
50%
U 142.5
U 142.5
51%
51%
J
1 pick
100%
predict
TAMU
will cover the spread
More markets
Updated
8 minutes ago
NCAAB • Texas Longhorns @ Gonzaga Bulldogs • West Regional - Second Round - Game 3
NCAAB • TEX @ GONZ
3/21 • 11:10PM
Sat, Mar 21 • 11:10PM
Texas Longhorns
TEX
10
Gonzaga Bulldogs
10
GONZ
Moneyline
Moneyline
31%
31%
69%
69%
Spread
Spread
+6.5
+6.5
52%
52%
-6.5
-6.5
50%
50%
Total
Total
O 147.5
O 147.5
50%
50%
U 147.5
U 147.5
52%
52%
J
1 pick
100%
predict
GONZ
will cover the spread
More markets
Updated
8 minutes ago
NCAAB • VCU Rams @ Illinois Fighting Illini • South Regional - Second Round - Game 3
NCAAB • VCU @ ILL
3/21 • 11:50PM
Sat, Mar 21 • 11:50PM
Virginia Commonwealth Rams
VCU
12
Illinois Fighting Illini
12
ILL
Moneyline
Moneyline
18%
18%
84%
84%
Spread
Spread
+11.5
+11.5
53%
53%
-11.5
-11.5
49%
49%
Total
Total
O 152.5
O 152.5
50%
50%
U 152.5
U 152.5
52%
52%
J
1 pick
100%
predict
ILL
will cover the spread
More markets
Updated
8 minutes ago
Tomorrow, March 22
NCAAB • Vanderbilt Commodores @ Nebraska Cornhuskers • South Regional - Second Round - Game 2
NCAAB • VAN @ NEB
3/22 • 12:45AM
Sun, Mar 22 • 12:45AM
16
Vanderbilt Commodores
16
VAN
14
Nebraska Cornhuskers
14
NEB
Moneyline
Moneyline
55%
55%
47%
47%
Spread
Spread
-1.5
-1.5
53%
53%
+1.5
+1.5
50%
50%
Total
Total
O 147.5
O 147.5
51%
51%
U 147.5
U 147.5
53%
53%
J
1 pick
100%
predict
NEB
will cover the spread
More markets
Updated
8 minutes ago
NCAAB • High Point Panthers @ Arkansas Razorbacks • West Regional - Second Round - Game 2
NCAAB • HPU @ ARK
3/22 • 1:45AM
Sun, Mar 22 • 1:45AM
High Point Panthers
HPU
15
Arkansas Razorbacks
15
ARK
Moneyline
Moneyline
15%
15%
87%
87%
Spread
Spread
+11.5
+11.5
51%
51%
-11.5
-11.5
52%
52%
Total
Total
O 169.5
O 169.5
50%
50%
U 169.5
U 169.5
53%
53%
J
1 pick
100%
predict
HPU
will cover the spread
More markets
Updated
8 minutes ago
NCAAB • Miami (FL) Hurricanes @ Purdue Boilermakers • West Regional - Second Round - Game 4
NCAAB • MIA @ PUR
3/22 • 4:10PM
Sun, Mar 22 • 4:10PM
23
Miami (FL) Hurricanes
23
MIA
13
Purdue Boilermakers
13
PUR
Moneyline
Moneyline
28%
28%
78%
78%
Spread
Spread
-
-
-
-
Total
Total
O 148.5
O 148.5
52%
52%
U 148.5
U 148.5
55%
55%
More markets
Updated
8 minutes ago
NCAAB • Kentucky Wildcats @ Iowa State Cyclones • Midwest Regional - Second Round - Game 4
NCAAB • UK @ ISU
3/22 • 6:45PM
Sun, Mar 22 • 6:45PM
Kentucky Wildcats
UK
6
Iowa State Cyclones
6
ISU
Moneyline
Moneyline
36%
36%
69%
69%
Spread
Spread
+5.5
+5.5
55%
55%
-5.5
-5.5
50%
50%
Total
Total
O 146.5
O 146.5
51%
51%
U 146.5
U 146.5
54%
54%
More markets
Updated
8 minutes ago
NCAAB • St. John's Red Storm @ Kansas Jayhawks • East Regional - Second Round - Game 2
NCAAB • SJU @ KU
3/22 • 9:15PM
Sun, Mar 22 • 9:15PM
9
St. John's Red Storm
9
SJU
17
Kansas Jayhawks
17
KU
Moneyline
Moneyline
63%
63%
41%
41%
Spread
Spread
-3.5
-3.5
53%
53%
+3.5
+3.5
53%
53%
Total
Total
-
-
-
-
More markets
Updated
8 minutes ago
NCAAB • Tennessee Volunteers @ Virginia Cavaliers • Midwest Regional - Second Round - Game 3
NCAAB • TENN @ UVA
3/22 • 10:10PM
Sun, Mar 22 • 10:10PM
25
Tennessee Volunteers
25
TENN
8
Virginia Cavaliers
8
UVA
Moneyline
Moneyline
54%
54%
48%
48%
Spread
Spread
-1.5
-1.5
51%
51%
+1.5
+1.5
52%
52%
Total
Total
O 137.5
O 137.5
53%
53%
U 137.5
U 137.5
53%
53%
More markets
Updated
8 minutes ago
NCAAB • Iowa Hawkeyes @ Florida Gators • South Regional - Second Round - Game 1
NCAAB • FLA @ IOWA
3/22 • 11:10PM
Sun, Mar 22 • 11:10PM
Iowa Hawkeyes
IOWA
4
Florida Gators
4
FLA
Moneyline
Moneyline
19%
19%
88%
88%
Spread
Spread
+10.5
+10.5
50%
50%
-10.5
-10.5
54%
54%
Total
Total
O 145.5
O 145.5
52%
52%
U 145.5
U 145.5
54%
54%
More markets
Updated
8 minutes ago
NCAAB • Utah State Aggies @ Arizona Wildcats • West Regional - Second Round - Game 1
NCAAB • USU @ ARIZ
3/22 • 11:50PM
Sun, Mar 22 • 11:50PM
Utah State Aggies
USU
2
Arizona Wildcats
2
ARIZ
Moneyline
Moneyline
14%
14%
88%
88%
Spread
Spread
+11.5
+11.5
50%
50%
-11.5
-11.5
51%
51%
Total
Total
O 156.5
O 156.5
52%
52%
U 156.5
U 156.5
53%
53%
More markets
Updated
8 minutes ago
Monday, March 23
NCAAB • UCLA Bruins @ UConn Huskies • East Regional - Second Round - Game 4
NCAAB • UCLA @ CONN
3/23 • 12:45AM
Mon, Mar 23 • 12:45AM
UCLA Bruins
UCLA
7
Connecticut Huskies
7
CONN
Moneyline
Moneyline
39%
39%
67%
67%
Spread
Spread
+4.5
+4.5
54%
54%
-4.5
-4.5
52%
52%
Total
Total
-
-
-
-
More markets
Updated
8 minutes ago
NCAAB • Texas Tech Red Raiders @ Alabama Crimson Tide • Midwest Regional - Second Round - Game 2
NCAAB • TTU @ ALA
3/23 • 1:45AM
Mon, Mar 23 • 1:45AM
19
Texas Tech Red Raiders
19
TTU
18
Alabama Crimson Tide
18
ALA
Moneyline
Moneyline
50%
50%
54%
54%
Spread
Spread
+0.5
+0.5
51%
51%
-0.5
-0.5
52%
52%
Total
Total
O 165.5
O 165.5
51%
51%
U 165.5
U 165.5
55%
55%
More markets
Updated
8 minutes ago